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Image Search Results
Journal: The Journal of organic chemistry
Article Title: Development of a Cell-Permeable Cyclic Peptidyl Inhibitor against the Keap1-Nrf2 Interaction
doi: 10.1021/acs.joc.9b02367
Figure Lengend Snippet: Biological activity of peptides 1 and 2. (a) Induction of luciferase expression by HepG2-ARE (Luc) cells by increasing concentrations of peptides 1 and 2. (b) Representative anti-Nrf2 western blot showing the effect of peptides 1 and 2 on the Nrf2 level in HEK293T cells. (c) Quantitation of western blots from (b). (d) Representative anti-HO-1 western blot showing the effect of peptides 1 and 2 on the HO-1 level in HEK293T cells. (e) Quantitation of western blots from (d). Data reported in (a), (c), and (e) represent the mean ± SD of at least three independent sets of experiments.
Article Snippet: The ARE
Techniques: Activity Assay, Luciferase, Expressing, Western Blot, Quantitation Assay